The Making of Nitric Oxide

Making Nitric Oxide

Chemistry:

2e- + C(NH2)2 + 3O2 → 2NO- + 2H2O + CO2

2e-
- :acids,
  - activated during niacin flush
  - many heating foods, spices
  - vinegar, citric acid, coffee
C(NH2)2
- :carbon attached to 2 amines
- quinine from
  - urea
  - arginine
  - creatine
  - metformin
  - others
3O2
- :three dioxides
- oxygen from breathing,
  - transported
  - Red Blood Cells
  - hemoglobin
  - iron bound by histidine
  - the H in SHUCA
→
- a controlled reaction
  - B1 thiamine
  - B2 riboflavin
  - B3 niacin flush
  - glutathione, cellular protection
  - calmodulin, calcium control
  - heme, histidine, (azole)
  - others
2NO-
- Nitric Oxide
- the active immune system
  - NOS - Nitric Oxide Species
    - eNOS - endothelial
    - nNOS - neruonal
    - iNOS - inducible
2H2O
- water
- breathed out to lose weight
CO2
- Carbon Dioxide
- breathed out to lose weigth

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Bottom note:

have no role in the nitrogenic immune system