Phenylalanine is the bait for the cancer cells to eat.
Phenylalanine alone will stimulate cancer cells to grow, avoid phenylalanine.
Inside the nano particle is a package of Nitric Oxide inducing moleules,
basically from free-nitrogen or the quinine rich molecule.
Nitric Oxide is a NOS [Nitric Oxide Species] which is one of the ROS [Reactive Oxygen Species]
This article is archived to avoid it disappearing from the Internet.
A chapter on NItric Oxide is also archived from
Harrison's: The Principles of Internal Medicine 14th Ed. 1998, Fauci et al.
Chapter 71
Note: In all subsequent printings of Harrison's the chapter on Nitric Oxide or any NOS never appears again, disappeared.
Nano particles and technology is to encase molecules inside of a lipid (oil) capsule for delivery.
Nitric Oxide (NO-) is the 'tool' white blood cells use to kill:
- tumors
- viruses
- parasites
- bacteria
- fungi
--- from https://on.rt.com/ar9m
‘Trojan horse’ treatment makes cancer self-destruct without use of drugs
28 Sep, 2020 10:40
A new experimental treatment reportedly tricks cancer cells into self-destructing, without the use of any drugs, providing new hope for winning the war on many different types of the disease.
The treatment involves a nanoparticle coated in an amino acid called L-phenylalanine. The chemical is not naturally produced in the body but is instead absorbed from meat and dairy produce that humans consume.
L-phenylalanine is the perfect bait as it is one of the main amino acids cancer cells require to grow and spread throughout the human body, wreaking havoc in the process.
The novel new treatment has proven incredibly successful on mice. The secret is the nanoparticle Nanoscopic phenylalanine Porous Amino Acid Mimic, or Nano-pPAAM for short.
Nano-pPAAM triggers overproduction of reactive oxygen species (ROS) which causes a cascade effect inside the cancer cells, killing them while leaving surrounding, healthy cells unharmed.
“Against conventional wisdom, our approach involved using the nanomaterial as a drug instead [of] as a drug-carrier,” says material scientist Dalton Tay from Nanyang Technological University in Singapore.
The method kills roughly 80 percent of breast, skin, and gastric cancer cells in mice, on par with leading chemotherapy treatments but without the nasty side effects. Research into nanoparticles typically focuses on using them as a delivery mechanism for drugs, not as the treatment itself.
There is still a long series of regulatory hurdles to surpass before the treatment will be available for human patients, however.
If it passes muster in clinical trials it will also help combat drug-resistant, recurring forms of cancer as well, providing yet another possible beacon of hope; without drugs to fight against, the cancer won’t have anything to resist.